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One of the most important vector-borne diseases is Zika virus infection. Although both are transmitted by the Aedes mosquito, the symptoms of the Zika virus (ZIKV) are milder than the symptoms of the dengue virus (DENV). However, the Zika virus poses a danger if infected in pregnant women, namely the risk of giving birth to babies with microcephaly defects. In this paper, we model the spread of Zika virus by involving the risk of babies born with microcephaly defects. Simulations and dynamic analysis performed on the model included basic reproduction ratios, stability of equilibrium points, and sensitivity analysis, especially in the microcephaly infant population.
Keyword: Zika, Microcephaly, mathematics model, vector-borne disease